Deviations from Hardy-Weinberg Equilibrium in Parental and Unaffected Sibling Genotype Data
نویسندگان
چکیده
منابع مشابه
Deviations from hardy-weinberg equilibrium in parental and unaffected sibling genotype data.
BACKGROUND Genotyping error can increase both type I and II errors. In order to elucidate potential genotyping errors, data quality control often includes testing genotype data for deviations from Hardy-Weinberg Equilibrium (HWE). METHODS The Hardy-Weinberg Disequilibrium (HWD) coefficient and the ability to reject the null hypothesis of HWE were calculated analytically for genotype data from...
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ژورنال
عنوان ژورنال: Human Heredity
سال: 2008
ISSN: 0001-5652,1423-0062
DOI: 10.1159/000179558